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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GUCY1A3
All Species:
11.21
Human Site:
S37
Identified Species:
20.56
UniProt:
Q02108
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02108
NP_000847.2
690
77452
S37
S
E
E
A
A
G
S
S
E
S
C
K
A
T
V
Chimpanzee
Pan troglodytes
XP_522169
734
81883
A55
P
S
P
A
A
A
A
A
A
A
A
A
A
P
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536590
746
83063
A67
P
A
P
A
P
A
P
A
A
C
S
S
S
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9ERL9
691
77555
S37
T
E
E
V
A
G
G
S
E
G
C
Q
A
T
L
Rat
Rattus norvegicus
P19686
690
77548
S37
I
E
E
V
A
G
V
S
E
S
C
Q
A
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510214
690
77963
S37
E
E
E
C
A
E
G
S
D
I
C
S
A
A
L
Chicken
Gallus gallus
XP_420375
688
77848
S37
E
K
D
C
T
E
N
S
S
R
A
A
L
P
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002667138
626
69572
G26
L
E
S
P
G
E
D
G
E
C
P
F
S
R
V
Tiger Blowfish
Takifugu rubipres
NP_001027855
675
75480
A37
E
Q
L
S
K
D
V
A
H
L
P
T
S
K
D
Fruit Fly
Dros. melanogaster
Q07093
676
75644
A37
D
E
E
L
S
D
D
A
L
T
L
T
H
L
Q
Honey Bee
Apis mellifera
NP_001011650
699
78655
G37
R
L
G
R
D
D
G
G
K
S
R
Q
S
S
F
Nematode Worm
Caenorhab. elegans
O02298
688
78384
D45
E
I
A
H
Y
Y
N
D
D
E
T
L
R
L
V
Sea Urchin
Strong. purpuratus
P16065
1125
126238
E210
R
D
Y
E
I
L
H
E
E
Y
Y
A
G
F
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.9
N.A.
47.3
N.A.
89.5
89.2
N.A.
87.5
84
N.A.
39.1
58.9
34.2
35
29.5
22.6
Protein Similarity:
100
63
N.A.
62.4
N.A.
94.9
94.9
N.A.
93.4
92.3
N.A.
54.3
73.6
53.3
55.3
48.2
36.3
P-Site Identity:
100
20
N.A.
6.6
N.A.
60
66.6
N.A.
40
6.6
N.A.
20
0
13.3
6.6
6.6
6.6
P-Site Similarity:
100
40
N.A.
26.6
N.A.
80
80
N.A.
53.3
33.3
N.A.
26.6
26.6
33.3
33.3
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
24
39
16
8
31
16
8
16
24
39
8
8
% A
% Cys:
0
0
0
16
0
0
0
0
0
16
31
0
0
0
0
% C
% Asp:
8
8
8
0
8
24
16
8
16
0
0
0
0
0
16
% D
% Glu:
31
47
39
8
0
24
0
8
39
8
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
8
% F
% Gly:
0
0
8
0
8
24
24
16
0
8
0
0
8
0
0
% G
% His:
0
0
0
8
0
0
8
0
8
0
0
0
8
0
0
% H
% Ile:
8
8
0
0
8
0
0
0
0
8
0
0
0
0
8
% I
% Lys:
0
8
0
0
8
0
0
0
8
0
0
8
0
8
0
% K
% Leu:
8
8
8
8
0
8
0
0
8
8
8
8
8
16
24
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
16
0
0
0
0
0
0
0
0
% N
% Pro:
16
0
16
8
8
0
8
0
0
0
16
0
0
16
0
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
0
24
0
0
8
% Q
% Arg:
16
0
0
8
0
0
0
0
0
8
8
0
8
8
0
% R
% Ser:
8
8
8
8
8
0
8
39
8
24
8
16
31
16
8
% S
% Thr:
8
0
0
0
8
0
0
0
0
8
8
16
0
24
0
% T
% Val:
0
0
0
16
0
0
16
0
0
0
0
0
0
0
24
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
8
8
0
0
0
8
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _